"Duphaston" when planning pregnancy

This medicine is produced in the form of tablets and has the main active ingredient - dydrogesterone, which in its chemical, pharmacological properties and molecular structure resembles a natural hormone produced by the body - progesterone.

But since it is not a derivative of testosterone - a natural hormone from the male "set" - it has no side effects of androgenic progestogens. It does not have negative properties - androgenic, estrogenic, anabolic and thermogenic activity, does not suppress hematopoietic functions, does not reduce metabolism and does not suppress liver function.


It is prescribed for endogenous progesterone deficiency, as it is beneficial affects the endometrium, does not allow hyperplasia to develop, stops excess estrogen. However, it does not affect reproductive functions, does not suppress the menstrual cycle. Does not affect conception and pregnancy.

The drug begins to act 2 hours after you received the dose, and finally and completely comes out after three full days.

Side effects are quite rare .

These include:

  • hemolytic anemia;
  • headache;
  • minor liver problems;
  • weakness;
  • abdominal pain;
  • allergic reactions;
  • pain in dairy glands;
  • breakthrough uterine bleeding.

If the last side effect occurs, then the drug should not be stopped, but rather increase the dose.

There is only one contraindication - individual intolerance.

Since "Duphaston" affects the hormonal sphere, it is undesirable to take it without a doctor's prescription. Self-medication can adversely affect egg maturation.

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"Duphaston" and ovulation

Ovulation is a natural physiological process that occurs in a healthy body of a woman of reproductive age, during which a mature follicle ruptures and an egg is released from it. It begins its way to the uterus through the fallopian tube.

If it meets at this time with a sperm, it is fertilized and implanted in the wall of the uterus, where future life will begin to develop. The meeting did not happen - you need to wait for the onset of the next menstrual cycle.

If conception has occurred, then the female body begins to intensively produce progesterone. When progesterone is insufficient, pregnancy ends in failurechno - the embryo is rejected.

That is why "Duphaston" is prescribed after the end of ovulation - so that pregnancy proceeded safely.

The hormone contained in the drug, replacing the natural one, does not allow the removal of the ovum from the uterine cavity, as it stops the contraction of its muscles.

When self-prescribing the drug, despite the fact that it is a substitute for a natural female hormone, pregnancy most often does not occur, although women believe that its use is to stimulate the production of an egg.

Why does this happen, does it suppress "Duphaston" ovulation? The synthetic analogue of progesterone does not interfere with cell production, but it can have an adverse effect on follicle maturation.

The effect of Duphaston on ovulation

The onset of pregnancy depends not only on the work of the hormonal system. Sometimes enough hormones are produced for the onset of this process, and the woman still goes to the doctors.

Reproductiveness depends on many factors, and the hormonal system is only one of the components, albeit the most important. The general condition of the body, the presence of genital infections, chronic diseases affect the course of pregnancy. Already after fertilization, pregnancy can be interrupted if the thyroid gland is disrupted, the blood structure changes, there are not enough nutrients for the formation of organic systems of the fetus - nature fights for the health of the offspring with its own, sometimes cruel methods, rejecting non-viable embryos.

When a woman , without seeking medical help, having read medical information and having seen enough of her friends who were helped by a hormonal agent to maintain a pregnancy, she begins to take it, but pregnancy does not occur, she falls into despair.

If she could imagine how affects "Duphaston" on ovulation, she would not make a mistake.

If the body produces enough progesterone, and pregnancy does not occur for other reasons, then instead ovulation stimulation "Dufaston" blocking it. Progesterone begins to be produced in the second half of the female menstrual cycle for a reason, after ovulation. If conception has occurred, then the body protects itself from such a process again.

Some mammals do not have this, and they always have a "fallback" . With the loss of one cub, the next pregnancy occurs, which may be delayed for some more time, if the period is unfavorable - lack of food or the female is in a state of stress.

Nature did not give such an ability to man, moreover, she took care of so that while the fetus is developing in the uterus - and for some time then outside of it - there is no repeated conception. Blocks subsequent ovaincreased production of progesterone.

As soon as the body stops producing it constantly, it returns to cyclicity, ovulation resumes.

Therefore, before prescribing "Duphaston », the gynecologist directs the woman for an ultrasound examination to determine if ovulation has occurred. And only then the drug is prescribed. In some cases, the day of ovulation is calculated based on the cycle of menstruation.

When their own progesterone is not enough, "Duphaston" drink from the first day of the cycle. The level of the hormone in the blood is determined by a blood test.

Indications for taking "Duphaston" and methods of application

Prescribe the drug in the following cases:

  • with infertility due to hormonal deficiency;
  • with a threat of miscarriage or recurrent miscarriage;
  • during breakthrough uterine bleeding;
  • for the treatment of endometriosis;
  • to eliminate menstrual pain and amenorrhea.

At the planning stage, the drug is prescribed from 15 to 24 days of the cycle. However, a competent gynecologist calculates the course of treatment individually after observing ovulation in dynamics. In the middle of the cycle, an ultrasound examination is performed, from which it is concluded whether the egg cell matures in the woman's body and, if so, when.

Usually, with this method of treatment, the desired pregnancy occurs quickly, but up to 20 obstetric weeks "Duphaston" is not canceled. This helps to prevent the abnormal development of the organic systems of the fetus - very often miscarriages occur when deviating from normal physiology - and to preserve the pregnancy, preventing the uterus from getting toned. Progesterone relaxes the muscles of the fetus.

The drug is also prescribed in the case when the pregnancy occurred on its own, and then the diagnosis is uterine hypertonicity.

Dosage and frequency reception "Duphaston" are specified depending on the diagnosis.

  • With a preventive purpose to prevent dysfunctional uterine bleeding - 2 times day 1 tablet from 11 to 25 days of the menstrual cycle;
  • Hormone replacement therapy - one tablet once a day at the same time, from 14 to 28 day of the cycle - the doctor himself chooses the period - combining with the intake estrogen;
  • Endometriosis - 2-3 tablets per day, from the 5th to the 25th day of the cycle, but a different regimen can be chosen;
  • Infertility - one tablet per day after ovulation up to the 25th day of the menstrual cycle. Treatment lasts up to six months, then take a break;
  • During pregnancy, with the threat of miscarriage - 4 tablets at once and then 1 tablet 3 times a day until the condition is completely stabilized. Another scheme can be used - 2 tablets per day until 20 weeks of pregnancy;
  • For PMS - 1 tablet 2 times a day from 11 to 25 days of the cycle;
  • Dysmenorrhea - 1 tablet 2 timesand on the day from 5 to 25 days of the menstrual cycle;
  • To stop breakthrough uterine bleeding, they drink "Duphaston" 2 times a day for a week.

Abrupt withdrawal of the drug is impossible - the dose is reduced gradually, the gynecologist explains how to do it correctly.

If you abruptly stop taking, you may experience a breakthrough uterine bleeding. In this case, pregnancy cannot be maintained.